产品货号：
Z16605
中文名称：
FKBP52/FKBP4抗体
英文名称：
Anti-FKBP52/FKBP4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FKBP52/FKBP4 Antibody |
| 指标别名 | 51kDa FK506 binding protein;52kDa FK506 binding protein;52kDa FKBP;59kDa immunophilin;FK506 binding protein 4;FK506 binding protein 4;59kDa;FKBP 4;FKBP 52;FKBP4;FKBP51;FKBP52;FKBP59;HBI;HSP binding immunophilin;Hsp56;Immunophilin FKBP52;p52;p59;PPIase;PPIase FKBP4;Rotamase |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | FKBP4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human FKBP52/FKBP4 (AVNDFELARADFQKVLQLY). |
| 实际分子量 | 52KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FK506-binding protein 4 is a protein that in humans is encoded by the FKBP4 gene.The protein encoded by this gene is a member of the immunophilin protein family,which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking.This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A),but unlike FKBP1A,this protein does not have immunosuppressant activity when complexed with FK506.It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase.It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines.Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy.The human genome contains several non-transcribed pseudogenes similar to this gene. |
| Uniprot ID | Q02790 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
| 基因名全称 | FKBP prolyl isomerase 4 |
| 蛋白名全称 | Peptidyl-prolyl cis-trans isomerase FKBP4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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